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Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus exposed to hydroxychloroquine

BACKGROUND: Based on the potential involvement of Toll-like receptor (TLR) signalling in the pathogenesis of neonatal lupus (NL), it was hypothesised that fetal exposure to hydroxychloroquine (HCQ), a TLR inhibitor, might reduce the risk of anti-SSA/Ro/SSB/La antibody-associated cardiac manifestatio...

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Detalhes bibliográficos
Main Authors: Izmirly, Peter M, Kim, Mimi Y, Llanos, Carolina, Le, Phuong U, Guerra, Marta M, Askanase, Anca D, Salmon, Jane E, Buyon, Jill P
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593727/
https://ncbi.nlm.nih.gov/pubmed/20447951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2009.119263
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