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Attenuation of saccharin-seeking in rats by orexin/hypocretin receptor 1 antagonist

RATIONALE: The orexin/hypocretin system has been implicated in reward-seeking, especially for highly salient food and drug rewards. We recently demonstrated that signaling at the OxR1 receptor is involved in sucrose reinforcement and reinstatement of sucrose-seeking elicited by sucrose-paired cues i...

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Autores principales: Cason, Angie M., Aston-Jones, Gary
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707982/
https://ncbi.nlm.nih.gov/pubmed/23494235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3051-7
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