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Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats

Behavioral economics is a powerful, translational approach for measuring drug demand in both humans and animals. Here, we asked if demand for cocaine in rats with limited drug experience could be used to identify individuals most at risk of expressing an addiction phenotype following either long- or...

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Pubblicato in:Eur J Neurosci
Autori principali: James, Morgan H., Bowrey, Hannah E., Stopper, Colin M., Aston-Jones, Gary
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083201/
https://ncbi.nlm.nih.gov/pubmed/30240516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14166
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