Overexpression of GATA1 Confers Resistance to Chemotherapy in Acute Megakaryocytic Leukemia

It has been previously shown that acute myeloid leukemia (AML) patients with higher levels of GATA1 expression have poorer outcomes. Furthermore, pediatric Down syndrome (DS) patients with acute megakaryocytic leukemia (AMKL), whose blast cells almost universally harbor somatic mutations in exon 2 o...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Caldwell, John Timothy, Edwards, Holly, Dombkowski, Alan A., Buck, Steven A., Matherly, Larry H., Ge, Yubin, Taub, Jeffrey W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707876/
https://ncbi.nlm.nih.gov/pubmed/23874683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068601
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