The Host-Encoded Heme Regulated Inhibitor (HRI) Facilitates Virulence-Associated Activities of Bacterial Pathogens

Here we show that cells lacking the heme-regulated inhibitor (HRI) are highly resistant to infection by bacterial pathogens. By examining the infection process in wild-type and HRI null cells, we found that HRI is required for pathogens to execute their virulence-associated cellular activities. Spec...

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Detalhes bibliográficos
Main Authors: Shrestha, Niraj, Boucher, Justin, Bahnan, Wael, Clark, Emily S., Rosqvist, Roland, Fields, Kenneth A., Khan, Wasif N., Schesser, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707855/
https://ncbi.nlm.nih.gov/pubmed/23874749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068754
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