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Insulin receptor membrane retention by a traceable chimeric mutant

BACKGROUND: The insulin receptor (IR) regulates glucose homeostasis, cell growth and differentiation. It has been hypothesized that the specific signaling characteristics of IR are in part determined by ligand-receptor complexes localization. Downstream signaling could be triggered from the plasma m...

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Detalhes bibliográficos
Main Authors: Giudice, Jimena, Jares-Erijman, Elizabeth A, Leskow, Federico Coluccio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707766/
https://ncbi.nlm.nih.gov/pubmed/23805988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-45
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