Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B

BACKGROUND: Insulin and insulin-like growth factors (IGFs) act on tetrameric tyrosine kinase receptors controlling essential functions including growth, metabolism, reproduction and longevity. The insulin receptor (IR) binds insulin and IGFs with different affinities triggering different cell respon...

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Detalhes bibliográficos
Main Authors: Giudice, Jimena, Barcos, Lucia Soledad, Guaimas, Francisco F, Penas-Steinhardt, Alberto, Giordano, Luciana, Jares-Erijman, Elizabeth A, Coluccio Leskow, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607927/
https://ncbi.nlm.nih.gov/pubmed/23497114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-18
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