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Structure-based Discovery of Antagonists of Nuclear Receptor LRH-1
Liver receptor homolog 1 (nuclear receptor LRH-1, NR5A2) is an essential regulator of gene transcription, critical for maintenance of cell pluripotency in early development and imperative for the proper functions of the liver, pancreas, and intestines during the adult life. Although physiological ho...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707686/ https://ncbi.nlm.nih.gov/pubmed/23667258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.411686 |
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