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Negative Regulation of the Acetyltransferase TIP60-p53 Interplay by UHRF1 (Ubiquitin-like with PHD and RING Finger Domains 1)

Numerous studies indicate the importance of acetylation in p53-mediated stress responses upon DNA damage. We and others previously showed that TIP60 (Tat-interacting protein of 60 kDa)-mediated acetylation of p53 at K120 is crucial for p53-dependent apoptotic responses. Nevertheless, it remains uncl...

詳細記述

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書誌詳細
主要な著者: Dai, Chao, Shi, Dingding, Gu, Wei
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707659/
https://ncbi.nlm.nih.gov/pubmed/23677994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476606
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