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Dynamics of the Antigen-binding Grooves in CD1 Proteins: REVERSIBLE HYDROPHOBIC COLLAPSE IN THE LIPID-FREE STATE

CD1 proteins mediate the presentation of endogenous and foreign lipids on the cell surface for recognition by T cell receptors. To sample a diverse antigen pool, CD1 proteins are repeatedly internalized and recycled, assisted, in some cases, by lipid transfer proteins such as saposins. The specifici...

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Bibliografiska uppgifter
Huvudupphovsmän: Garzón, Diana, Anselmi, Claudio, Bond, Peter J., Faraldo-Gómez, José D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707654/
https://ncbi.nlm.nih.gov/pubmed/23677998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470179
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