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Dynamics of the Antigen-binding Grooves in CD1 Proteins: REVERSIBLE HYDROPHOBIC COLLAPSE IN THE LIPID-FREE STATE
CD1 proteins mediate the presentation of endogenous and foreign lipids on the cell surface for recognition by T cell receptors. To sample a diverse antigen pool, CD1 proteins are repeatedly internalized and recycled, assisted, in some cases, by lipid transfer proteins such as saposins. The specifici...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707654/ https://ncbi.nlm.nih.gov/pubmed/23677998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470179 |
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