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Role of lipid trimming and CD1 groove size in cellular antigen presentation
Cellular CD1 proteins bind lipids that differ in length (C(12−80)), including antigens that exceed the capacity of the CD1 groove. This could be accomplished by trimming lipids to a uniform length before loading or by inserting each lipid so that it penetrates the groove to a varying extent. New ass...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1500985/ https://ncbi.nlm.nih.gov/pubmed/16794581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601185 |
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