Conserved Gating Elements in TRPC4 and TRPC5 Channels

TRPC4 and TRPC5 proteins share 65% amino acid sequence identity and form Ca(2+)-permeable nonselective cation channels. They are activated by stimulation of receptors coupled to the phosphoinositide signaling cascade. Replacing a conserved glycine residue within the cytosolic S4–S5 linker of both pr...

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Main Authors: Beck, Andreas, Speicher, Tilman, Stoerger, Christof, Sell, Thomas, Dettmer, Viviane, Jusoh, Siti A., Abdulmughni, Ammar, Cavalié, Adolfo, Philipp, Stephan E., Zhu, Michael X., Helms, Volkhard, Wissenbach, Ulrich, Flockerzi, Veit
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2013
主題:
Signal Transduction
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707650/
https://ncbi.nlm.nih.gov/pubmed/23677990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.478305
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