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Interleukin-1β up-regulates RGS4 through the canonical IKK2/IκBα/NF-κB pathway in rabbit colonic smooth muscle

Initial Ca(2+)-dependent contraction of the intestinal smooth muscle mediated by G(q)-coupled receptors is attenuated by RGS4 (regulator of G-protein signalling 4). Treatment of colonic muscle cells with IL-1β (interleukin-1β) inhibits acetylcholine-stimulated initial contraction through increasing...

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Hlavní autoři: Wenhui, HU, Fang, LI, Mahavadi, Sunila, Murthy, Karnam S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707494/
https://ncbi.nlm.nih.gov/pubmed/18260825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20080042
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