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Interleukin-1 Receptor and Caspase-1 Are Required for the Th17 Response in Nitrogen Dioxide–Promoted Allergic Airway Disease

Nitrogen dioxide (NO(2)) is an environmental pollutant and endogenously generated oxidant associated with the development, severity, and exacerbation of asthma. NO(2) exposure is capable of allergically sensitizing mice to the innocuous inhaled antigen ovalbumin (OVA), promoting neutrophil and eosin...

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Autori principali: Martin, Rebecca A., Ather, Jennifer L., Lundblad, Lennart K. A., Suratt, Benjamin T., Boyson, Jonathan E., Budd, Ralph C., Alcorn, John F., Flavell, Richard A., Eisenbarth, Stephanie C., Poynter, Matthew E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707382/
https://ncbi.nlm.nih.gov/pubmed/23371061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0423OC
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