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Effect of Zileuton and Celecoxib on Urinary LTE(4) and PGE-M Levels in Smokers
Cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) utilize arachidonic acid for the synthesis of eicosanoids that have been implicated in carcinogenesis and cardiovascular disease. The ability of celecoxib, a selective COX-2 inhibitor, to redirect arachidonic acid into the 5-LO pathway can potential...
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Main Authors: | , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2013
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707304/ https://ncbi.nlm.nih.gov/pubmed/23682075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0083 |
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