Levels of Prostaglandin E Metabolite, the Major Urinary Metabolite of Prostaglandin E(2), Are Increased in Smokers

PURPOSE: Increased levels of cyclooxygenase-2 and prostaglandin E(2) (PGE(2)) have been observed in tobacco-related malignancies of the upper aerodigestive tract. Moreover, exposure to tobacco smoke can stimulate the synthesis of PGE(2). Recent evidence suggests that urinary PGE metabolite (PGE-M) c...

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Autores principales: Gross, Neil D., Boyle, Jay O., Morrow, Jason D., Williams, Myles K., Moskowitz, Chaya S., Subbaramaiah, Kotha, Dannenberg, Andrew J., Duffield-Lillico, Anna J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939807/
https://ncbi.nlm.nih.gov/pubmed/16115954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-05-0733
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