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A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest
The Rb/E2F pathway is deregulated in virtually all human tumors. It is clear that, in addition to Rb itself, essential co-factors required for transcriptional repression and silencing of E2F target genes are mutated or lost in cancer. To identify novel co-factors required for Rb/E2F-mediated inhibit...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707121/ https://ncbi.nlm.nih.gov/pubmed/22249253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.622 |
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