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A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest

The Rb/E2F pathway is deregulated in virtually all human tumors. It is clear that, in addition to Rb itself, essential co-factors required for transcriptional repression and silencing of E2F target genes are mutated or lost in cancer. To identify novel co-factors required for Rb/E2F-mediated inhibit...

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Bibliografische gegevens
Hoofdauteurs: Angus, Steven P., Nevins, Joseph R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707121/
https://ncbi.nlm.nih.gov/pubmed/22249253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.622
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