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A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest
The Rb/E2F pathway is deregulated in virtually all human tumors. It is clear that, in addition to Rb itself, essential co-factors required for transcriptional repression and silencing of E2F target genes are mutated or lost in cancer. To identify novel co-factors required for Rb/E2F-mediated inhibit...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707121/ https://ncbi.nlm.nih.gov/pubmed/22249253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.622 |
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