Isoform level expression profiles provide better cancer signatures than gene level expression profiles

BACKGROUND: The majority of mammalian genes generate multiple transcript variants and protein isoforms through alternative transcription and/or alternative splicing, and the dynamic changes at the transcript/isoform level between non-oncogenic and cancer cells remain largely unexplored. We hypothesi...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, ZhongFa, Pal, Sharmistha, Bi, Yingtao, Tchou, Julia, Davuluri, Ramana V
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706752/
https://ncbi.nlm.nih.gov/pubmed/23594586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm437
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