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The Many Spaces of uPAR: Delivery of Theranostic Agents and Nanobins to Multiple Tumor Compartments through a Single Target

The urokinase plasminogen activator (uPA) system is a proteolytic system comprised of uPA, a cell surface receptor for uPA (uPAR), and an inhibitor of uPA (PAI-1) and is implicated in many aspects of tumor growth and metastasis. The uPA system has been identified in nearly all solid tumors examined...

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Autors principals: O'Halloran, Thomas V., Ahn, Richard, Hankins, Patrick, Swindell, Elden, Mazar, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706693/
https://ncbi.nlm.nih.gov/pubmed/23843897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.4953
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