Urokinase Plasminogen Activator System Targeted Delivery of Nanobins as a Novel Ovarian Cancer Therapeutics

The urokinase system is overexpressed in epithelial ovarian cancer (OvCa) cells and is expressed at low levels in normal cells. To develop a platform for intracellular and targeted delivery of therapeutics in OvCa, we conjugated urokinase plasminogen activator (uPA) antibodies to liposomal nanobins....

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Autors principals: Zhang, Yilin, Kenny, Hilary A., Swindell, Elden P., Mitra, Anirban K., Hankins, Patrick L., Ahn, Richard W., Gwin, Katja, Mazar, Andrew P., O’Halloran, Thomas V., Lengyel, Ernst
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885360/
https://ncbi.nlm.nih.gov/pubmed/24061648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0204
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