IFN-γ and TNF-α Synergistically Induce Mesenchymal Stem Cell Impairment and Tumorigenesis via NFκB Signaling

An inflammatory microenvironment may cause organ degenerative diseases and malignant tumors. However, the precise mechanisms of inflammation-induced diseases are not fully understood. Here we show that the proinflammatory cytokines interferon γ (IFN-γ) and tumor necrosis factor α (TNF-α) synergistic...

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Библиографические подробности
Главные авторы: Wang, Lei, Zhao, Yinghua, Liu, Yi, Akiyama, Kentaro, Chen, Chider, Qu, Cunye, Jin, Yan, Shi, Songtao
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706580/
https://ncbi.nlm.nih.gov/pubmed/23553791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1388
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