Mesenchymal Stem Cell-Based Tissue Regeneration is Governed by Recipient T Lymphocyte via IFN-γ and TNF-α

Stem cell-based regenerative medicine is a promising approach for tissue reconstruction. Here, we showed that pro-inflammatory T cells in the recipients inhibited bone marrow mesenchymal stem cell (BMMSC)-mediated bone formation via T helper 1 (Th1) cytokine interferon (IFN)-γ induced down-regulatio...

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Bibliografiske detaljer
Main Authors: Liu, Yi, Wang, Lei, Kikuiri, Takashi, Akiyama, Kentaro, Chen, Chider, Xu, Xingtian, Yang, Ruili, Chen, WanJun, Wang, Songlin, Shi, Songtao
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233650/
https://ncbi.nlm.nih.gov/pubmed/22101767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2542
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