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Cell-Based Immunotherapy With Mesenchymal Stem Cells Cures Bisphosphonate-Related Osteonecrosis of the Jaw–like Disease in Mice

Patients on high-dose bisphosphonate and immunosuppressive therapy have an increased risk of bisphosphonate-related osteonecrosis of the jaw (BRONJ); despite the disease severity, its pathophysiology remains unknown, and appropriate therapy is not established. Here we have developed a mouse model of...

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Main Authors: Kikuiri, Takashi, Kim, Insoo, Yamaza, Takyoshi, Akiyama, Kentaro, Zhang, Qunzhou, Li, Yunsheng, Chen, Chider, Chen, WanJun, Wang, Songlin, Le, Anh D, Shi, Songtao
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154005/
https://ncbi.nlm.nih.gov/pubmed/20200952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.37
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