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CIRCADIAN CLOCK PERIOD INVERSELY CORRELATES WITH ILLNESS SEVERITY IN CELLS FROM PATIENTS WITH ALCOHOL USE DISORDERS

BACKGROUND: Clinical and genetic studies suggest circadian clock genes may contribute to biological mechanisms underlying alcohol use disorders (AUD). In particular, the Per2 gene regulates alcohol consumption in mutant animals, and in humans with AUD, the 10870 variant in PER2 has been associated w...

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Bibliografische gegevens
Hoofdauteurs: McCarthy, Michael J., Fernandes, Malcolm, Kranzler, Henry R., Covault, Jonathan M., Welsh, David K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706548/
https://ncbi.nlm.nih.gov/pubmed/23550834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12106
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