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CIRCADIAN CLOCK PERIOD INVERSELY CORRELATES WITH ILLNESS SEVERITY IN CELLS FROM PATIENTS WITH ALCOHOL USE DISORDERS

BACKGROUND: Clinical and genetic studies suggest circadian clock genes may contribute to biological mechanisms underlying alcohol use disorders (AUD). In particular, the Per2 gene regulates alcohol consumption in mutant animals, and in humans with AUD, the 10870 variant in PER2 has been associated w...

詳細記述

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書誌詳細
主要な著者: McCarthy, Michael J., Fernandes, Malcolm, Kranzler, Henry R., Covault, Jonathan M., Welsh, David K.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706548/
https://ncbi.nlm.nih.gov/pubmed/23550834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12106
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