Zoledronic Acid Enhances Lipopolysaccharide-Stimulated Proinflammatory Reactions through Controlled Expression of SOCS1 in Macrophages

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious side effect of nitrogen-containing bisphosphonate (NBP) use. Many studies have shown that BRONJ is limited to the jawbone and does not occur in the other bones. We hypothesized that BRONJ is related to local bacterial iections and...

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Detalhes bibliográficos
Main Authors: Muratsu, Daichi, Yoshiga, Daigo, Taketomi, Takaharu, Onimura, Tomohiro, Seki, Yoshihiro, Matsumoto, Akinobu, Nakamura, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706453/
https://ncbi.nlm.nih.gov/pubmed/23874464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067906
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