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Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production
Suppressor of cytokine signaling-3 (SOCS3) has multiple functions including inhibition of Janus kinase activity, regulation of protein degradation, and suppression of cytokine signaling. SOCS3 modulates macrophage response to cytokines such as IL-6 and leptin that are systemically induced in obesity...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196771/ https://ncbi.nlm.nih.gov/pubmed/21751240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23267 |
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