Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages.
We have isolated an 18-kDa peptide (designated sp18, for 18-kDa secreted protein) from the conditioned medium of lipopolysaccharide-stimulated RAW 264.7 murine macrophages. Purified sp18 had in vivo inflammatory activity and in vitro chemotactic activity for human peripheral blood polymorphonuclear...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1565646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3511 |
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