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Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages.

We have isolated an 18-kDa peptide (designated sp18, for 18-kDa secreted protein) from the conditioned medium of lipopolysaccharide-stimulated RAW 264.7 murine macrophages. Purified sp18 had in vivo inflammatory activity and in vitro chemotactic activity for human peripheral blood polymorphonuclear...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Sherry, B, Yarlett, N, Strupp, A, Cerami, A
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1992
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1565646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3511
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