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Extracellular ATP Released by Osteoblasts Is A Key Local Inhibitor of Bone Mineralisation

Previous studies have shown that exogenous ATP (>1µM) prevents bone formation in vitro by blocking mineralisation of the collagenous matrix. This effect is thought to be mediated via both P2 receptor-dependent pathways and a receptor-independent mechanism (hydrolysis of ATP to produce the mineral...

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Hlavní autoři: Orriss, Isabel R., Key, Michelle L., Hajjawi, Mark O. R., Arnett, Timothy R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706437/
https://ncbi.nlm.nih.gov/pubmed/23874866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069057
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