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Acidosis Is a key regulator of osteoblast ecto‐nucleotidase pyrophosphatase/phosphodiesterase 1 (NPP1) expression and activity
Previous work has shown that acidosis prevents bone nodule formation by osteoblasts in vitro by inhibiting mineralisation of the collagenous matrix. The ratio of phosphate (P(i)) to pyrophosphate (PP(i)) in the bone microenvironment is a fundamental regulator of bone mineralisation. Both P(i) and PP...
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| Pubblicato in: | J Cell Physiol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4549203/ https://ncbi.nlm.nih.gov/pubmed/26033523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25041 |
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