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Structural Analysis of Mitochondrial Mutations Reveals a Role for Bigenomic Protein Interactions in Human Disease
Mitochondria are the energy producing organelles of the cell, and mutations within their genome can cause numerous and often severe human diseases. At the heart of every mitochondrion is a set of five large multi-protein machines collectively known as the mitochondrial respiratory chain (MRC). This...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706435/ https://ncbi.nlm.nih.gov/pubmed/23874847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069003 |
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