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Structural Analysis of Mitochondrial Mutations Reveals a Role for Bigenomic Protein Interactions in Human Disease

Mitochondria are the energy producing organelles of the cell, and mutations within their genome can cause numerous and often severe human diseases. At the heart of every mitochondrion is a set of five large multi-protein machines collectively known as the mitochondrial respiratory chain (MRC). This...

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Detalhes bibliográficos
Main Authors: Lloyd, Rhiannon E., McGeehan, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706435/
https://ncbi.nlm.nih.gov/pubmed/23874847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069003
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