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The Extracellular Microenvironment Explains Variations in Passive Drug Transport across Different Airway Epithelial Cell Types

PURPOSE: We sought to identify key variables in cellular architecture and physiology that might explain observed differences in the passive transport properties of small molecule drugs across different airway epithelial cell types. METHODS: Propranolol (PR) was selected as a weakly basic, model comp...

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Detalhes bibliográficos
Main Authors: Min, Kyoung Ah, Talattof, Arjang, Tsume, Yasuhiro, Stringer, Kathleen A., Yu, Jing-yu, Lim, Dong Hyun, Rosania, Gus R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706189/
https://ncbi.nlm.nih.gov/pubmed/23708857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1069-5
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