Cryo-EM Structure of a Group II Chaperonin in the Prehydrolysis ATP-Bound State Leading to Lid Closure

Chaperonins are large ATP-driven molecular machines that mediate cellular protein folding. Group II chaperonins use their “built-in lid” to close their central folding chamber. Here we report the structure of an archaeal group II chaperonin in its prehydrolysis ATP-bound state at subnanometer resolu...

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Detalhes bibliográficos
Main Authors: Zhang, Junjie, Ma, Boxue, DiMaio, Frank, Douglas, Nicholai R., Joachimiak, Lukasz A., Baker, David, Frydman, Judith, Levitt, Michael, Chiu, Wah
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705922/
https://ncbi.nlm.nih.gov/pubmed/21565698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.03.005
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