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Cytotoxic antibodies to cloned rat islet cells in serum of patients with diabetes mellitus.
We have found complement-dependent cytotoxic antibodies in the serum of 8 of 24 patients with insulin-dependent diabetes mellitus using a 51Cr cytotoxicity assay with monolayers of cloned rat islet cells (clones RINm 5F and RINm 14B). In contrast, complement-dependent cytotoxicity with 51Cr release...
Gespeichert in:
| Veröffentlicht in: | J Clin Invest |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
1981
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370581/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7007435/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110048 |
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