Cytotoxic antibodies to cloned rat islet cells in serum of patients with diabetes mellitus.

We have found complement-dependent cytotoxic antibodies in the serum of 8 of 24 patients with insulin-dependent diabetes mellitus using a 51Cr cytotoxicity assay with monolayers of cloned rat islet cells (clones RINm 5F and RINm 14B). In contrast, complement-dependent cytotoxicity with 51Cr release...

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Detaylı Bibliyografya
Asıl Yazarlar: Eisenbarth, G S, Morris, M A, Scearce, R M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1981
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC370581/
https://ncbi.nlm.nih.gov/pubmed/7007435
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