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Cytotoxic antibodies to cloned rat islet cells in serum of patients with diabetes mellitus.

We have found complement-dependent cytotoxic antibodies in the serum of 8 of 24 patients with insulin-dependent diabetes mellitus using a 51Cr cytotoxicity assay with monolayers of cloned rat islet cells (clones RINm 5F and RINm 14B). In contrast, complement-dependent cytotoxicity with 51Cr release...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Eisenbarth, G S, Morris, M A, Scearce, R M
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1981
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370581/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7007435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110048
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