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Production and characterization of a cytotoxic monoclonal antibody reacting with rat islet cells.

We have produced a murine monoclonal antibody (F43 A1D2) that binds to the cell surface of both rat islet tumor cells (RINm clone 5F and RINm clone 14B) and normal rat islet cells. This antibody is cytotoxic in the presence of complement for RIN tumor cells as well as A, B, and D pancreatic polypept...

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Autors principals: Crump, M A, Scearce, R, Dobersen, M, Kortz, W, Eisenbarth, G S
Format: Artigo
Idioma:Inglês
Publicat: 1982
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC370269/
https://ncbi.nlm.nih.gov/pubmed/7050174
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