GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death

Increased glucose catabolism and resistance to cell death are hallmarks of cancers, but the link between them remains elusive. Remarkably, under conditions where caspases are inhibited, the process of cell death is delayed but rarely blocked, leading to the occurrence of caspase-independent cell dea...

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Detalhes bibliográficos
Main Authors: Jacquin, M A, Chiche, J, Zunino, B, Bénéteau, M, Meynet, O, Pradelli, L A, Marchetti, S, Cornille, A, Carles, M, Ricci, J-E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705596/
https://ncbi.nlm.nih.gov/pubmed/23645209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.32
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