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Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response

Most DNA-damaging agents are weak inducers of an anticancer immune response. Increased glycolysis is one of the best-described hallmarks of tumor cells; therefore, we investigated the impact of glycolysis inhibition, using 2-deoxyglucose (2DG), in combination with cytotoxic agents on the induction o...

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Hlavní autoři: Bénéteau, Marie, Zunino, Barbara, Jacquin, Marie A., Meynet, Ophélie, Chiche, Johanna, Pradelli, Ludivine A., Marchetti, Sandrine, Cornille, Aurore, Carles, Michel, Ricci, Jean-Ehrland
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523878/
https://ncbi.nlm.nih.gov/pubmed/23169636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206360109
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