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Angiotensin II AT(2) receptor decreases AT(1) receptor expression and function via nitric oxide/cGMP/Sp1 in renal proximal tubule cells from Wistar–Kyoto rats

BACKGROUND: The renin–angiotensin (Ang) system controls blood pressure, in part, by regulating renal tubular sodium transport. In the kidney, activation of the angiotensin II type 1 (AT(1)) receptor increases renal sodium reabsorption, whereas the angiotensin II type 2 (AT(2)) receptor produces the...

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Detalhes bibliográficos
Main Authors: Yang, Jian, Chen, Caiyu, Ren, Hongmei, Han, Yu, He, Duofen, Zhou, Lin, Hopfer, Ulrich, Jose, Pedro A., Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705562/
https://ncbi.nlm.nih.gov/pubmed/22504846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e3283532099
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