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Activation of D(4) dopamine receptor decreases AT(1) angiotensin II receptor expression in rat renal proximal tubule cells

The dopaminergic and renin angiotensin systems interact to regulate blood pressure. Disruption of the D(4) dopamine receptor gene in mice produces hypertension that is associated with increased renal AT(1) receptor expression. We hypothesize that the D(4) receptor can inhibit AT(1) receptor expressi...

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Dettagli Bibliografici
Pubblicato in:Hypertension
Autori principali: Chen, Ken, Deng, Kun, Wang, Xiaoyan, Wang, Zhen, Zheng, Shuo, Ren, Hongmei, He, Duofen, Han, Yu, Asico, Laureano D., Jose, Pedro A., Zeng, Chunyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268176/
https://ncbi.nlm.nih.gov/pubmed/25368031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04038
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