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Activation of D(4) dopamine receptor decreases AT(1) angiotensin II receptor expression in rat renal proximal tubule cells

The dopaminergic and renin angiotensin systems interact to regulate blood pressure. Disruption of the D(4) dopamine receptor gene in mice produces hypertension that is associated with increased renal AT(1) receptor expression. We hypothesize that the D(4) receptor can inhibit AT(1) receptor expressi...

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Bibliografiska uppgifter
I publikationen:Hypertension
Huvudupphovsmän: Chen, Ken, Deng, Kun, Wang, Xiaoyan, Wang, Zhen, Zheng, Shuo, Ren, Hongmei, He, Duofen, Han, Yu, Asico, Laureano D., Jose, Pedro A., Zeng, Chunyu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268176/
https://ncbi.nlm.nih.gov/pubmed/25368031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04038
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