Activation of D(4) dopamine receptor decreases AT(1) angiotensin II receptor expression in rat renal proximal tubule cells

The dopaminergic and renin angiotensin systems interact to regulate blood pressure. Disruption of the D(4) dopamine receptor gene in mice produces hypertension that is associated with increased renal AT(1) receptor expression. We hypothesize that the D(4) receptor can inhibit AT(1) receptor expressi...

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Vydáno v:Hypertension
Hlavní autoři: Chen, Ken, Deng, Kun, Wang, Xiaoyan, Wang, Zhen, Zheng, Shuo, Ren, Hongmei, He, Duofen, Han, Yu, Asico, Laureano D., Jose, Pedro A., Zeng, Chunyu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268176/
https://ncbi.nlm.nih.gov/pubmed/25368031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04038
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