Activation of D(4) dopamine receptor decreases AT(1) angiotensin II receptor expression in rat renal proximal tubule cells

The dopaminergic and renin angiotensin systems interact to regulate blood pressure. Disruption of the D(4) dopamine receptor gene in mice produces hypertension that is associated with increased renal AT(1) receptor expression. We hypothesize that the D(4) receptor can inhibit AT(1) receptor expressi...

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Published in:Hypertension
Main Authors: Chen, Ken, Deng, Kun, Wang, Xiaoyan, Wang, Zhen, Zheng, Shuo, Ren, Hongmei, He, Duofen, Han, Yu, Asico, Laureano D., Jose, Pedro A., Zeng, Chunyu
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268176/
https://ncbi.nlm.nih.gov/pubmed/25368031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04038
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