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Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.
Hydroxyurea, a widely used cytotoxic/cytostatic agent that does not influence methylation of DNA bases, increases fetal hemoglobin production in anemic monkeys. To determine its effect in sickle cell anemia, we treated two patients with a total of four, 5-d courses (50 mg/kg per d, divided into thre...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6205021/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111464 |
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