Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1

Little is known about how a neuron undergoes site-specific changes in intrinsic excitability during neuronal activity. We provide evidence for a novel mechanism for mTORC1 kinase–dependent translational regulation of the voltage-gated potassium channel Kv1.1 messenger RNA (mRNA). We identified a mic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sosanya, Natasha M., Huang, Peggy P.C., Cacheaux, Luisa P., Chen, Chun Jung, Nguyen, Kathleen, Perrone-Bizzozero, Nora I., Raab-Graham, Kimberly F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704988/
https://ncbi.nlm.nih.gov/pubmed/23836929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201212089
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados