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Prediction of gene–phenotype associations in humans, mice, and plants using phenologs

BACKGROUND: Phenotypes and diseases may be related to seemingly dissimilar phenotypes in other species by means of the orthology of underlying genes. Such “orthologous phenotypes,” or “phenologs,” are examples of deep homology, and may be used to predict additional candidate disease genes. RESULTS:...

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Detalhes bibliográficos
Main Authors: Woods, John O, Singh-Blom, Ulf Martin, Laurent, Jon M, McGary, Kriston L, Marcotte, Edward M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704650/
https://ncbi.nlm.nih.gov/pubmed/23800157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-203
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