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Systematic discovery of nonobvious human disease models through orthologous phenotypes
Biologists have long used model organisms to study human diseases, particularly when the model bears a close resemblance to the disease. We present a method that quantitatively and systematically identifies nonobvious equivalences between mutant phenotypes in different species, based on overlapping...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851946/ https://ncbi.nlm.nih.gov/pubmed/20308572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910200107 |
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