Prostacyclin biosynthesis in cultured vascular endothelium is limited by deactivation of cyclooxygenase.

Primary monolayer cultures of human umbilical vein endothelium produce prostacyclin (PGI2) in response to stimulation by thrombin, ionophore A23187, arachidonic acid, and the prostaglandin endoperoxide, PGH2. None of these treatments had a significant effect on the capacity of the endothelium to pro...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Brotherton, A F, Hoak, J C
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1983
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6415107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111081
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