Prostacyclin biosynthesis in cultured vascular endothelium is limited by deactivation of cyclooxygenase.
Primary monolayer cultures of human umbilical vein endothelium produce prostacyclin (PGI2) in response to stimulation by thrombin, ionophore A23187, arachidonic acid, and the prostaglandin endoperoxide, PGH2. None of these treatments had a significant effect on the capacity of the endothelium to pro...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1983
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6415107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111081 |
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